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::: HGH Information and Clinical Research
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A
Brief History of HGH Research
Human
growth hormone was first discovered in 1956 and it's structure was
identified in 1972. Before synthetic HGH molecules were genetically
engineered in 1998, HGH was extracted from cadavers and then injected with
needles into the human body.
Over the past 3 decades, there have
been a growing number of clinical research studies investigating the
capabilities and purported benefits of the human growth
hormone.
Many researchers have concluded that one of the primary
causes of aging is the decrease of HGH human growth hormone
production.
According to Dr. Ronald Klatz, M.D., President of the
American Academy of Anti-Aging Medicine, "Aging appears to be due in large
part to the drastic decline of growth hormone in the body after
adulthood."
According to HGH human growth hormone research, at age
21, the normal level of circulating HGH is about 10 milligrams per
deciliter of blood, but at age 61, it's decreased 80% to only 2
milligrams. It is believed that growth hormone is what grows the cells,
bones, muscles and organs, and it is the level of growth hormone after age
30 that slowly robs us of our youth.
After age 30, the secretion
rate of HGH drops approximately 14% per decade. By 80, most people barely
produce enough HGH to build a fingernail, explaining why injuries
experienced by seniors take so long to heal.
HGH
Human Growth Hormone Research - Clinical Studies
The New
England Journal of Medicine published the clinical findings of Daniel
Rudman, MD, regarding his HGH human growth hormone research on the
anti-aging effects of HGH. His findings were astonishing.
Dr.
Rudman studied patients age 61 to 81 at the Medical College of
Wisconsin-Milwaukee. After six months, Dr. Rudman observed a reversal of
the aging process from 10 to 20 years in the patients who received HGH
injections. But in the control group (those who didn't receive HGH
injections), the normal aging process continued.
Other HGH human
growth hormone clinical research studies performed over the past 30 years
have demonstrated that HGH can allow users to lose fat, build muscle mass,
improve sexual performance, remove wrinkles, reduce cellulite and increase
immune function. HGH is the master hormone which is secreted by the
pituitary gland and is responsible for directly and indirectly balancing
the body's critical hormones.
Human
Growth Hormone - Clinical Research Conclusions
"The
effects of six months of human growth hormone on lean body mass and
adipose-tissue were equivalent in magnitude to the changes incurred during
10-20 years of aging." Daniel Rudman, M.D., New England Journal of
Medicine
"It is possible that chronic physiologic GH and/or
IGF-I replacement therapy might reverse (or prevent) some of these
"inevitable" sequelae of aging." (Study of GH therapy in the elderly -
March 1992.) V.A. Medical Center and Department of Medicine,
Stanford University Medical Center
"Replacement therapy with
Growth Hormone has shown beneficial/normalizing effect on parameters such
as cardiac and renal function, thyroid hormone metabolism, bone
metabolism, sweat secretion, total and regional fuel metabolism and
psychological well being..." Dr. Jorgensen and Dr. Christian of
Copenhagen, Denmark, in European Journal of Endocrinology,
1994
"We really have something here which may be able to
reverse some of the problems associated with aging." Dr. Anthony
Karpos, M.D.
"Daily Administration of human growth hormone in
the first week after trauma would enhance the metabolic status...
resulting in reduced morbidity and earlier discharge from hospital." (May
1992, Journal of Surgery. Vol 111, 495-502.) Drs. Ramias, Shamos,
and Schiller of St. Joseph Hospital Medical Center in Phoenix,
AZ
"All adults with growth hormone deficiency should now be
considered for growth hormone replacement therapy." (1995) Dr. Jake
Powrie, M.D. and Dr. Andrew Weissberger, St. Thomas Hospital, London
England
"There is no evidence suggestion that Growth Hormone
Replacement Therapy causes any unfavorable long term side effects."
(Hormone Research, 1995) Dr. Rosen, M.D. and Dr. G. Johannsson, M.D.
of University Hospital, Goteborg, Sweden
References Cited:
- Salomon F, Cuneo RC, Hesp R et al. The Effects of Treatment with
Recombinant Human Growth Hormone on Body Composition and Metabolism in
Adults with Growth Hormone Deficiency. New England Journal of Medicine
1989;321:1797-1803.
- Bengtsson BA. The Consequences of Growth Hormone Deficiency in
Adults. Acta Endocrinologica 1993;128 (Suppl 2):2-5.
- Cuneo RC, Salomon F, Wiles CM et al. Growth Hormone Treatment in
Growth Hormone Deficient Adults. II. Effects on Exercise Performance.
Journal of Applied Physiology 1991;70:695-700.
- O'Halloran DJ, Tsatsoulis A, Whitehouse RW et al. Increased Bone
Density after Recombinant Human Growth Hormone (GH) Therapy in Adults
with Isolated GH Deficiency. Journal of Clinical Endocrinology and
Metabolism 1993;76:1344-1348.
- McGauley GA, Cuneo RC, Salomon F et al. Psychological Well-Being
Before and After Growth Hormone Treatment in Adults with Growth Hormone
Deficiency. Hormone Research 1990;33 (suppl 4):52-54.
- Bengtsson BA, Eden S, Lonn L et al. Treatment of Adults with Growth
Hormone (GH) Deficiency with Recombinant Human GH. Journal of Clinical
Endocrinology and Metabolism 1993;76;309-317.
- Johnston DG, Bengtsson BA. Workshop Report: the Effects of Growth
Hormone and Growth Hormone Deficiency on Lipids and the Cardiovascular
System. Acta Endocrinologica 1993;128 (Suppl 2): 69-70.
- Amato G, Carella C, Fazio S et al. Body Composition, Bone
Metabolism, and Heart Structure and Function in Growth Hormone
(GH)-Deficient Adults Before and After GH Replacement Therapy at Low
Doses. Journal of Clinical Endocrinology and Metabolism
1993;77:1671-1676.
- Standford University Medical Center (Psycho-Neuro Endocrinology,
VOl. 17, no. 4, 1992
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